Suggestions by @user_26273
12,275 suggestions

Michelle Pfeiffer
as Lady Jessica in Dune (1991 - 1994)

F. Murray Abraham
as Shaddam IV, the Padishah Emperor in Dune (1991 - 1994)

James Earl Jones
as Thurfir Hawat in Dune (1991 - 1994)

Johnny Depp
as Paul Atreides in Dune (1991 - 1994)

Javier Botet
as Nightmare in Marvel Cinematic Universe

Sophie Thatcher
as Anne Marie in Marvel Cinematic Universe

Sophie Thatcher
as Sin in Marvel Cinematic Universe

Javier Bardem
as Knull in Marvel Cinematic Universe

Bryce Dallas Howard
as Pepper Potts in Marvel Villains and Heroes (no actors that have played them before)

Timothy Olyphant
as Iron Man/ Tony Stark in Marvel Villains and Heroes (no actors that have played them before)

Javier Bardem
as Knull in Marvel Villains and Heroes (no actors that have played them before)

Tanner Buchanan
as Jason Todd in Batman VIII

Robert Downey Jr.
as Haymitch Abernathy in Hunger Games Reboot

Gillian Anderson
as President Coin in Hunger Games Reboot

Charles Dance
as President Snow in Hunger Games Reboot

Bill Hader
as Ceasar Flickerman in Hunger Games Reboot

Forrest Goodluck
as Gale Hawthorne in Hunger Games Reboot

Amber Midthunder
as Katniss Everdeen in Hunger Games Reboot

Michael Wincott
as Admiral Hackett in Mass Effect

Denzel Washington
as Kang the Conqueror in Ant-Man and the Wasp: Quantumania (2013)