Suggestions by @nathanielpreston1
23,165 suggestions
Gargamel
as Best Cartoon Villain in Best & Worst of Cartoons.
Cobra Commander
as Best Cartoon Villain in Best & Worst of Cartoons.
Skeletor
as Best Cartoon Villain in Best & Worst of Cartoons.
Slade
as Best Cartoon Villain in Best & Worst of Cartoons.
Queen Chrysalis
as Best Cartoon Villain in Best & Worst of Cartoons.
Kingpin (Spider-Man 1994)
as Best Cartoon Villain in Best & Worst of Cartoons.
Dr. Heinz Doofenshmirtz
as Best Cartoon Villain in Best & Worst of Cartoons.
Sheldon J. Plankton
as Best Cartoon Villain in Best & Worst of Cartoons.
Yami Marik
as Best Cartoon Villain in Best & Worst of Cartoons.
Mojo Jojo
as Best Cartoon Villain in Best & Worst of Cartoons.
Mozenrath
as Best Cartoon Villain in Best & Worst of Cartoons.
Yami Bakura
as Best Cartoon Villain in Best & Worst of Cartoons.
Denzel Crocker
as Best Cartoon Villain in Best & Worst of Cartoons.
Cell (Dragon Ball)
as Best Cartoon Villain in Best & Worst of Cartoons.
Lex Luthor (DCAU)
as Best Cartoon Villain in Best & Worst of Cartoons.
Aku (samurai jack)
as Best Cartoon Villain in Best & Worst of Cartoons.
Team Rocket Trio (Jessie, James, and Meowth)
as Best Cartoon Villain in Best & Worst of Cartoons.
Sideshow Bob
as Best Cartoon Villain in Best & Worst of Cartoons.
Frieza
as Best Cartoon Villain in Best & Worst of Cartoons.
Joker (DCAU)
as Best Cartoon Villain in Best & Worst of Cartoons.