Suggestions by @nathanielpreston1
23,165 suggestions
Sideshow Bob
as Best Evil Laugh in Best & Worst Of Cartoons
Shredder 2003
as Best Evil Laugh in Best & Worst Of Cartoons
The Joker (Animated)
as Best Evil Laugh in Best & Worst Of Cartoons
Ultron (Marvel Animated Universe)
as Best Cartoon Villain in Best & Worst Of Cartoons
Mr Freeze (BTAS)
as Best Cartoon Villain in Best & Worst Of Cartoons
Grimmel the Grisly
as Best Cartoon Villain in Best & Worst Of Cartoons
Dwayne LaFontant (The Verminator)
as Best Cartoon Villain in Best & Worst Of Cartoons
Brainiac (DCAU)
as Best Cartoon Villain in Best & Worst Of Cartoons
Stinky Pete (The Prospector)
as Best Cartoon Villain in Best & Worst Of Cartoons
Chef Skinner
as Best Cartoon Villain in Best & Worst Of Cartoons
Chick Hicks
as Best Cartoon Villain in Best & Worst Of Cartoons
Yokai (Professor Robert Callaghan)
as Best Cartoon Villain in Best & Worst Of Cartoons
Gallaxhar
as Best Cartoon Villain in Best & Worst Of Cartoons
Tighten (Hal Stewart)
as Best Cartoon Villain in Best & Worst Of Cartoons
Mother Gothel
as Best Cartoon Villain in Best & Worst Of Cartoons
Doctor Octopus (SMTAS)
as Best Cartoon Villain in Best & Worst Of Cartoons
Zira
as Best Cartoon Villain in Best & Worst Of Cartoons
Rameses
as Best Cartoon Villain in Best & Worst Of Cartoons
Dick Dastardly
as Best Cartoon Villain in Best & Worst Of Cartoons
The Toad (Flushed Away)
as Best Cartoon Villain in Best & Worst Of Cartoons