Suggestions by @matthewchadd

Pat Hingle

as Uncle Ben in Tim Burton's Spider-Man (1990's)

Dianne Wiest

as Aunt May in Tim Burton's Spider-Man (1990's)

Jennifer Connelly

as Mary Jane Watson in Tim Burton's Spider-Man (1990's)

Samuel L. Jackson

as Max Dillion in Tim Burton's Spider-Man (1990's)

Jeff Goldblum

as Dr. Curt Connors in Tim Burton's Spider-Man (1990's)

Michelle Pfeiffer

as Helen Stacy in Tim Burton's Spider-Man (1990's)

Christopher Lloyd

as Adrian Toomes in Tim Burton's Spider-Man (1990's)

Robert De Niro

as Dr. Otto Octavius in Tim Burton's Spider-Man (1990's)

Werner Herzog

as Dr. Otto Octavius in Tim Burton's Spider-Man (1990's)

Tom Cruise

as Harry Osborn in Tim Burton's Spider-Man (1990's)

Michael Ironside

as Flint Marko in Tim Burton's Spider-Man (1990's)

Anthony Michael Hall

as Eddie Brock in Tim Burton's Spider-Man (1990's)

Michael Keaton

as Captain George Stacy in Tim Burton's Spider-Man (1990's)

R. Lee Ermey

as J Jonah Jameson in Tim Burton's Spider-Man (1990's)

Sharon Stone

as Felicia Hardy in Tim Burton's Spider-Man (1990's)

Johnny Depp

as Dr. Otto Octavius in Tim Burton's Spider-Man (1990's)

Sarah Jessica Parker

as Betty Brant in Tim Burton's Spider-Man (1990's)

Christopher Walken

as Norman Osborn in Tim Burton's Spider-Man (1990's)

Winona Ryder

as Gwen Stacy in Tim Burton's Spider-Man (1990's)

Michael J. Fox

as Peter Parker in Tim Burton's Spider-Man (1990's)