Suggestions by @kipwalker

John Debney

as Composer in Calvin and Hobbes

Rose Byrne

as Calvin's Mom in Calvin and Hobbes

Domhnall Gleeson

as Mr. Tibbs in The BFG

Tim Burton

as Director in The BFG

Rachel McAdams

as Annie Hughes in Iron Giant

Margot Robbie

as Aeon Flux in Æon Flux

J.K. Simmons

as General Mandible in Antz

Melonie Díaz

as Azteca in Antz

Dwayne Johnson

as Weaver in Antz

Rose Byrne

as Princess Atta in A Bug's Life

Carey Mulligan

as Elsie Ethrington in The Flying Nun

Denzel Washington

as Col.Kurtz in Dreamcatcher

Jillian Bell

as Sandy Cheeks in Spongebob Squarepants

Nicholas Stoller

as Director in Spongebob Squarepants

Alan Arkin

as Barnacle Boy in Spongebob Squarepants

Ed Asner

as Mermaid Man in Spongebob Squarepants

John Cena

as Larry in Spongebob Squarepants

Chloë Grace Moretz

as Pearl Krabs in Spongebob Squarepants

Frank Welker

as Gary in Spongebob Squarepants

Kathy Bates

as Mrs. Puff in Spongebob Squarepants