Suggestions by @jasleenfaydelarosa

Neve Campbell

as Felicity Ferne in Nowhere Girls (Nowhere Boys 90's Genderswap)

Olivia D'Abo

as Jess Tracy in Thunderbirds are Go (90's Genderswap)

Charlotte Ayanna

as Brains in Thunderbirds are Go (90's Genderswap)

James Van Der Beek

as Sir Philip in Thunderbirds are Go (90's Genderswap)

John Cho

as Tanush "Kayo" Kyrano in Thunderbirds are Go (90's Genderswap)

Sarah Michelle Gellar

as Jane Tracy in Thunderbirds are Go (90's Genderswap)

Alicia Silverstone

as Georgia Tracy in Thunderbirds are Go (90's Genderswap)

Neve Campbell

as Virginia Tracy in Thunderbirds are Go (90's Genderswap)

Samantha Langevin

as Jess Tracy in Thunderbirds are Go (80s Genderswap)

William Zabka

as Sir Philip in Thunderbirds are Go (80s Genderswap)

Valerie Hartman

as Alana Tracy in Thunderbirds are Go (80s Genderswap)

Winona Ryder

as Virginia Tracy in Thunderbirds are Go (80s Genderswap)

Lori Loughlin

as Sara Tracy in Thunderbirds are Go (80s Genderswap)

Elisabeth Shue

as Jane Tracy in Thunderbirds are Go (80s Genderswap)

Christopher Atkins

as Andrew Gibbs in Sex Education (80s Genderswap)

Rachel Blanchard

as Clara Matthews in Skandar and the Unicorn Thief (90's Live Action)

Robert Zemeckis

as Director in Thunderbirds are Go (80s Genderswap)

BD Wong

as Tanush "Kayo" Kyrano in Thunderbirds are Go (80s Genderswap)

Olivia D'Abo

as Georgia Tracy in Thunderbirds are Go (80s Genderswap)

Jenna Dewan

as Abby Stevenson in The Babysitters Club (2000's Live Action)