Suggestions by @grissol

Burt Reynolds

as Iron Man 1980s in Marvel/DC characters in Different Decades

Tom Cruise

as Iron Man 2000s in Marvel/DC characters in Different Decades

Starro

as Sequids in Invincible Characters replaced by DC characters

Black Lightning

as Black Samson in Invincible Characters replaced by DC characters

Lex Luthor

as DA Sinclair in Invincible Characters replaced by DC characters

Amanda Waller

as Cecil Stedman in Invincible Characters replaced by DC characters

Plastic Man

as Shapesmith in Invincible Characters replaced by DC characters

Martian Manhunter

as Martian Man in Invincible Characters replaced by DC characters

Roy Harper (Speedy/Arsenal)

as Rex Splode in Invincible Characters replaced by DC characters

Koriand'r/Kory Andrews (Starfire)

as Atom Eve in Invincible Characters replaced by DC characters

Lois Lane

as Debbie Grayson in Invincible Characters replaced by DC characters

Iris West

as Olga in Invincible Characters replaced by DC characters

Blue Beetle (Jaime Reyes)

as Tech Jacket in Invincible Characters replaced by DC characters

Jon Kent

as Oliver in Invincible Characters replaced by DC characters

Superboy (Conner Kent)

as Invincible in Invincible Characters replaced by DC characters

Batman (Dick Grayson)

as Darkwing II in Invincible Characters replaced by DC characters

Cyborg (Victor Stone)

as Robot in Invincible Characters replaced by DC characters

Green Lantern (Jessica Cruz)

as Green Ghost (Show) in Invincible Characters replaced by DC characters

Hal Jordan (Green Lantern)

as Green Ghost (Comic) in Invincible Characters replaced by DC characters

Aquaman

as Aquarus in Invincible Characters replaced by DC characters