Suggestions by @giannirodriguez

Angelina Jolie

as Lois Griffin in Family Guy

Zoe Saldaña

as Lois Griffin in Family Guy

Jessica Chastain

as Lois Griffin in Family Guy

Tara Strong

as Lois Griffin in Family Guy

Charlize Theron

as Lois Griffin in Family Guy

Eva Green

as Lois Griffin in Family Guy

Rachel McAdams

as Lois Griffin in Family Guy

Kristen Wiig

as Lois Griffin in Family Guy

Amy Adams

as Lois Griffin in Family Guy

Elizabeth Moss

as Lois Griffin in Family Guy

Christina Ricci

as Lois Griffin in Family Guy

Rose Byrne

as Lois Griffin in Family Guy

Laura Prepon

as Lois Griffin in Family Guy

Zooey Deschanel

as Lois Griffin in Family Guy

Rebel Wilson

as Lois Griffin in Family Guy

Robert Downey Jr.

as Peter Griffin in Family Guy

Joaquin Phoenix

as Peter Griffin in Family Guy

Dwayne Johnson

as Peter Griffin in Family Guy

Andy Serkis

as Peter Griffin in Family Guy

Ralph Fiennes

as Peter Griffin in Family Guy