Suggestions by @fancastunity

Nicolas Cage

as "Dr. Octavius" in The Spectacular Spider-Man

Spoiler

as "Dr. Octavius" in The Spectacular Spider-Man

Mahershala Ali

as "I'll Be Keeping An Eye on You" in The Spectacular Spider-Man

Spoiler

as "I'll Be Keeping An Eye on You" in The Spectacular Spider-Man

Kyle MacLachlan

as Ben Parker in The Spectacular Spider-Man

Ethan Hawke

as Norman Osborn in The Spectacular Spider-Man

Natalia Dyer

as Betty Brant in The Spectacular Spider-Man

Michael Beach

as Robbie Robertson in The Spectacular Spider-Man

Edgar Ramírez

as George Stacy in The Spectacular Spider-Man

Talia Ryder

as Liz Allan in The Spectacular Spider-Man

Sam Rechner

as Flash Thompson in The Spectacular Spider-Man

Jon Hamm

as J. Jonah Jameson in The Spectacular Spider-Man

Sarah Snook

as Dr. Martha Connors in The Spectacular Spider-Man

Matthew Macfadyen

as The Lizard in The Spectacular Spider-Man

Naomi Watts

as May Parker in The Spectacular Spider-Man

Dominic Sessa

as Harry Osborn in The Spectacular Spider-Man

Jenna Ortega

as Gwen Stacy in The Spectacular Spider-Man

Gabriel LaBelle

as Spider-Man in The Spectacular Spider-Man

Maya Erskine

as The Wasp in Ant-Man and the Wasp: A Tale To Astonish

Maya Erskine

as The Wasp in The Avengers: Earth's Mightiest Heroes!