Suggestions by @chasestucki
23,210 suggestions
Hugh Laurie
as Dr Curt Connors (2002-2007) in Spider-Man (2002-2021)
Brad Pitt
as Flint Marko (2007,2021) in Spider-Man (2002-2021)
John Travolta
as Dr Otto Octavius (2004,2021) in Spider-Man (2002-2021)
Bryan Cranston
as Norman Osborn (2002-2007,2021) in Spider-Man (2002-2021)
Tom Hanks
as Uncle Ben (2012) in Spider-Man (2002-2021)
Sean Connery
as Uncle Ben (2002-2007) in Spider-Man (2002-2021)
Maggie Smith
as Aunt May (2002-2007) in Spider-Man (2002-2021)
Mary Steenburgen
as Aunt May (2012-2014) in Spider-Man (2002-2021)
Courteney Cox
as Aunt May (2017-2021) in Spider-Man (2002-2021)
Vince Vaughn
as Happy Hogan in Spider-Man (2002-2021)
Jessica Chastain
as Pepper Potts in Spider-Man (2002-2021)
Ethan Hawke
as Dr Stephen Strange in Spider-Man (2002-2021)
Denzel Washington
as Nick Fury in Spider-Man (2002-2021)
Hugh Jackman
as Tony Stark (2017-2019) in Spider-Man (2002-2021)
Rico Rodriguez
as Ned Leeds in Spider-Man (2002-2021)
China Anne McClain
as Michelle Jones in Spider-Man (2002-2021)
Robert Pattinson
as Harry Osborn (2014) in Spider-Man (2002-2021)
Chris Evans
as Harry Osborn (2002-2007) in Spider-Man (2002-2021)
Johanna Braddy
as Gwen Stacy (2012-2014) in Spider-Man (2002-2021)
Kristen Bell
as Gwen Stacy (2007) in Spider-Man (2002-2021)