Susan "Mandark" Astronomanov is the main antagonist in Dexter's Laboratory. He is Dexter's rival and later mortal nemesis who often seeks to destroy both Dexter and his lab to prove once and for all that he is the superior genius.
The villains in fictional universes have some things that almost trump the good guys. Excellent actors, catchy songs, and even some awesome tech and weaponry. Cast any villain fitting the categories below, and what they have.