In another universe... similar to william and henry swap roles... instead of knives hatred towards humanity... vash has hatred towards humanity due to his biological older sister's death by filthy scum medical humans. Vash killed and sabotage people in the ship especially rem.
Knives finds put about his twin brother's hatred towards humans. Knives betrayed his younger twin brother and vash finds out and became furios and mad. He decided to ripped of his twin brother's arm but... he was blasted out.