Shiro (シロ, Shiro) is a childhood friend of Ganta Igarashi and Hagire Rinichirō's adopted daughter. Sorae Igarashi and Hagire experimented on her in order to gain insight in how to heighten a person's immune system.
This experimentation unintentionally caused Shiro to become the very first Deadman. Shiro developed a second personality called the Wretched Egg (レチッドエッグ, Rechiddo Eggu) or the Red Man (赤い男, Akai Otoko) in order to cope with her suffering.