When Romeo steals the plans for the Universe Portal Machine, he constructs his own version of the device to recruit an inter-dimensional band of villains made up of Green Goblin, Sideshow Bob, and Melvin Sneddly. Known as The Syndicate of Evil), they create a Doomsday Device, while unleashing an army on the worlds.
a plan.
With a plan, Catboy and the other Power Heroes uses their Universe Portal Machine to scour the multiverse for drafting the heroes of Captain Underpants, Simpsons and Spidey and his Amazing Friends. Now the heroes must defeat both The Evil Syndicate and destroy the Doomsday Machine.