male
Susan "Mandark" Astronomanov is the main antagonist in Dexter's Laboratory. He is Dexter's rival and later mortal nemesis who often seeks to destroy both Dexter and his lab to prove once and for all that he is the superior genius.
Mandark Astronomonov
Christopher Mintz-Plasse
for Christopher Mintz-Plasse in This Is The End (Cartoon Network)
Suggested by themegacaster
Recasting this is the end with CN Characters