Miles Morales, now in college, has taken the mantle of Spider-Man after Peter Parker retired to spend more time with his wife, Mary Jane, & his newborn daughter, Mayday. Miles is not sure whether to tell his parents he's Spider-Man or not. A new villain who has a big hatred towards Miles and somehow knows he's Spider-Man starts targeting everyone he cares about. Spider-Man must stop this new villain and learn that anyone can wear the mask. (Based on Miles Morales: Spider-Man Vol 2. #1-5)