35 years in the past, the children at the Sisters of Mercy Orphanage are playing soccer with an old soda can in the front yard. But then, Sister Mary-Mengele, the meanest and strictest nun in the orphanage gets their attention by telling them to go inside and do their work. Later, infant versions of Moe, Larry, and Curly are dumped on the doorstep of the orphanage from an unknown person's car. Ever since, the trio has wreaked havoc in the place, leaving the nuns who run it utterly terrified, especially Sister Mary-Mengele, who has always hated the trio.
