Bernadette "Bernie" Skampersky is a daring 12-year-old rodent with a dream. Ever since she witnessed the murder of her beloved big brother Brody, she's been trying to join the Mouse Watch, an elite group of high-tech international crimefighters/do-gooders organized by Gadget. When the Watch finally recruits Bernie, she's paired up with another rookie, a nerdy teenage rat named Jarvis Slinktail — which she has a hard time accepting because a rat killed Brody, which has made her prejudiced against the entire species. However, Bernie and Jarvis are forced to work together when their training is interrupted by an emergency which leaves the fate of the world in their paws.
