Months after Drakovia resisted the invasion, the Monster Squad is finally at full strength, which will be essential given the daunting challenge awaiting its members. Accidentally awakened by overly curious researchers, some of the major Aztec "deities" have returned to our world, determined to "reboot" it as it should have happened over a decade ago. The Squad members are warned of the danger by Archangel Raphaelle, the first archangel to return to Earth after millennia, a sign of the importance of the approaching battle. However, Lord Holmwood of Prodigium, determined to handle things "the human way," sends some hunters and numerous mercenaries to finish off the Squad and claim the glory ! Once again, those who look like monsters are actually the ones who appear the most...human.