In 1900, in the cotton country of the deep South, beautiful and brilliant Regina Hubbard Giddens struggles for wealth and freedom within the confines of an early 20th-century society where fathers only considered sons as legal heirs. As a result, thanks to their ruthless tradesman father, her avaricious brothers, Benjamin and Oscar, are independently wealthy, while she is financially dependent upon her sickly husband, Horace, whose severe heart condition has confined him to a sanitarium in Baltimore for several years.