Set in Japan predominantly during the late 1990s, The Garden of Sinners follows the story of Shiki Ryougi (両儀式, Ryōgi Shiki), a teenage girl raised as a demon hunter who acquired the "Mystic Eyes of Death Perception" after surviving a fatal accident. It also chronicles Mikiya Kokutou's unwavering efforts to get closer to her when they were still high school students and their adventures later on in dealing with supernatural cases as investigators for Touko Aozaki's detective agency, Garan no Dou.
