The Fantastic Four are back as they encounter strange beings known as Inhumans, who are discriminated by humans like mutants are. They offer to help the Royal Family stop Maximus from sparking a war between humans & Inhumans. Dr. Doom, who is now the ruler of his home country Latveria, returns and joins Maximus with secret plans of his own to destroy the Fantastic Four. (Based on Fantastic Four Vol. 1 #45-47)