female
Harley Quinn, real name Harleen Quinzel, was the sidekick and on-off girlfriend of the Joker. She occasionally struck out on her own, and often served as a companion and accomplice to Poison Ivy.
Harley Quinn (DCAU)
1992
for 1992 in The Best Villains of the Years
Suggested by toonking1985
Who do you think is the best villain (from movies, television, video games, comics, stories, etc.) from each year?
