After the mysterious disappearance of his parents, teenage outcast Peter Parker is raised by his Uncle Ben and Aunt May in Queens, New York. Now a high school student and science whiz, Peter stumbles upon a hidden briefcase belonging to his father, leading him to Oscorp Industries and his father’s former partner, Dr. Curt Connors. While snooping around Oscorp, Peter is bitten by a genetically modified spider, granting him superhuman abilities like strength, agility, wall-crawling, and a “spider-sense.” As Peter learns to harness his powers, tragedy strikes when Uncle Ben is killed, inspiring Peter to become the vigilante known as Spider-Man. Meanwhile, Dr. Connors—desperate to regrow his missing arm—tests a serum derived from reptilian DNA on himself, transforming into the monstrous Lizard. With New York in danger, Spider-Man must rise to stop Connors’ plan to mutate the entire city, all while balancing a budding romance with Gwen Stacy, the daughter of NYPD Captain George Stacy, who’s leading the manhunt for Spider-Man.
