In a world where physical appearance can be "downloaded" and swapped via bio-synthetic skins, Dr. Juno Sante is the Chief Aesthetic Officer for L'Image, the world’s most powerful beauty conglomerate. The show explores the dark side of a society that has reached "peak perfection." When a "glitch" begins causing users' original faces to bleed through their synthetic ones, Juno is tasked with a cover-up that leads her to a cult of "Originalists"—people who refuse to alter their natural features. Juno's loyalty is tested when her own synthetic skin begins to fail, revealing a face she hasn't seen in fifteen years.