The Substance (2024) is a body horror film about fading Hollywood star Elisabeth Sparkle (Demi Moore) who uses a black-market serum to create a younger, perfect version of herself (Margaret Qualley, named Sue), requiring them to alternate consciousness weekly, leading to a terrifying exploration of beauty standards, aging, self-worth, and addiction as the aging body deteriorates and Sue's fame grows, exposing the destructive pursuit of eternal youth
