Peter Parker's life is perfect: he's a senior in high school, he has a girlfriend, he's a science genius who works with Dr Connors, he works at the Daily Bugle, but above all, he's the amazing Spider-Man. Norman Osborn is proud of Peter, but his life isn't so perfect because Oscorp is in crisis. A certain "Big Man" wants to help Osborn in exchange for Spider-Man's head. Osborn goes mad and transforms into the Green Goblin. Meanwhile Dr Connors develops a cure for his lacking arm, but this substance transforms Connors into Lizard. Meanwhile, Dr. Connors develops a cure for his missing arm, but it transforms him into the Lizard. Osborn decides to team up with Big Man and founds the Sinister Six to kill Spider-Man. Peter's life is soon torn apart by his enemies as he begins to lose everything: his best friend Harry feels betrayed and disappears, Connors loses his identity due to his obsession, and lastly Green Goblin kills the girl who loves, Gwen Stacy. At the end of the story, Peter runs away from the one he loves and promises himself that he will always be just Spider-Man, no more Petr Parker.