4 and and half mouths after the events of the previous film, Peter Parker find himself dons the costume, one last time when Norman become the Green Goblin, again and breaks Dr. Octopus, the Sandman, the Rhino, and his thug, the Shocker out of prison and being Electro to life where they become the Sinister Six where they plans on killing Spider-Man, once and for all. Now, Spider-Man must survive the wrath of his six enemies and save New York City.