Vulture, electro, sandman, shocker, rhino and doctor octopus, led by the new green goblin, is planing a big fight against Spider-Man. They were joined by many villains that Spider-Man put away during the spectacular Spider-Man series, such as venom, craven hunter, mysterio, and many more. Spider-Man was having lunch with friends like hulk, iron man, newly introduced miles morales, and many more when Jay Johna Jameson calls Pete and tells him that the sinister 6 and many others that he put away in 2008-2009 recently broke out and they need pictures for the bugle. Harry has been acting strangely after Norm passed away, and he’s been wanting a little revenge on Spider-Man. Gwen, being worried about Harry, notices the globuine green that Harry kept using in the spectacular Spider-Man series, has been hiding more of It in his locker. Pete, who graduated the year before they do, after Harry did something to prevent the others from graduating, had no idea this was happening. Gwen then calls Pete wondering if he’s seen Harry because she hasn’t heard from him in the past 4 days. In the middle of the conversation the new green goblin arrives. Pete is in shock because he knew Spider-Man defeated him last time. But something is different about this green goblin. Liz is still upset with Pete after they broke up. While all that was happening, harry was still planing revenge on Spider-Man, when the sinister 6 and all the other bad guys ask him to break them out. Harry, knows it’s wrong but he decides to go it. Can Spider-Man and his new friends save midtown and the rest of New York from the villains?