Miles Morales was a street kid from Harlem when he was on a field trip to Oscorp when he was bitten by a radioactive spider. This was a knockoff of the stark industries spider that but Peter Parker so it had other side effects as well. He seeks help from the original Spider-Man and the Harlem Hero, Luke Cage, to learn how to become a superhero protecting the streets of Harlem. Then multiple new villains arise on the streets of Harlem with similar technology, getting it from an arms dealer called The Tinkerer
