Teenager Miles Morales struggles to live up to the expectations of his father, Officer Jefferson Davis, who sees Spider-Man as a threat. Miles moves to boarding school, but after school he usually runs off to his uncle Aaron Davis' house. When he takes Miles to an abandoned subway station to graffiti the walls, Miles is bitten by a radioactive spider and gains spider skills.
Miles returns to the station to look for the spider and finds a particle accelerator called "The Super-Collider" built by Wilson Fisk, who plans to access parallel universes to find alternative versions of his late wife and son, who died in a car accident afterwards that they found him trying to kill Spider-Man. Spider-Man tries to deactivate the collider while fighting the police of Fisk, a giant mutant version of the Green Goblin and the Sneaker. Spider-Man saves Miles and realizes their similarities. The Goblin pushes the Spider into the collider, causing an explosion that almost kills him. Injured, Spider-Man gives Miles a USB device to disable the accelerator and warns
