New York City teenager Miles Morales struggles to live up to the expectations of his father, police officer Jefferson Davis, who sees Spider-Man as a menace. Miles adjusts to prep school, and visits his uncle Aaron Davis, who takes him to an abandoned subway station to paint graffiti. Miles is bitten by a radioactive spider and gains spider-like abilities similar to Spider-Man.
Returning to the station, Miles discovers a collider built by Wilson Fisk, who hopes to access parallel universes to bring back his late wife and son, whose deaths he blames on Spider-Man. Miles watches as Spider-Man attempts to disable the collider while fighting Wilson's henchmen, Green Goblin and the Prowler. Spider-Man saves Miles, but Green Goblin shoves Spider-Man into the collider, causing an explosion that kills Goblin and severely wounds Spider-Man. Spider-Man gives Miles a USB flash drive designed to disable the collider, warning that the machine could destroy the city if reactivated. After watching in horror as Wilson kills Spider-Man, Miles flees with Prowler in pursuit, eventually getting away.
