Spider-Man/Deadpool is a 50-issue comic book series published by Marvel Comics from 2016 to 2019. The title characters, Spider-Man and Deadpool, shared the focus of the book. The comic was originally launched by Joe Kelly and Ed McGuinness, but many authors and artists worked on the series during its run. Spider-Man/Deadpool is an action-comedy that explores the dynamic between the two characters and their personality differences.