Peter Parker tries to fix his relationship with MJ, since his past relationships with her didn't work so well. Dr. Curt Connors subsequently loses his arm in an accident, and tries to fix it with DNA from a lizard. This works for a minute, but then it spirals out of control, and he turns into The Lizard. Adrian Toomes develops giant tech wings to start a life of crime, when he is stopped by Spider-Man. Full of hatred, he goes goes full-out on him. Peter will have to face some of the greatest threats he has ever encountered.
