The movie is a rags to riches story. It begins in Harlem, New York, in 1958, and follows the girl group, Sister and the Sisters, which is made up of three sisters: Sister, Sparkle, and Delores. Stix, Sparkle's love interest and the group's manager, is able to help bring the group from "amateur nights to brief stardom before tragedy (dope, melancholia, the wrong man)" ensues and the group splits.