"My Friend Dario" is the first single from Vitalic's debut album, OK Cowboy. It is the first single from Vitalic to use "Brigitte", a vocal synthesis program. "No Fun", which is another track on OK Cowboy, also uses Brigitte. The music video for "My Friend Dario" features a band mimicking instrumentation; the guitarists play air guitar and the drummer air drums. The lack of band instruments in the video reflect a statement made on Vitalic's website; that the instruments on his album OK Cowboy are entirely synthesized and that "the only thing he can't fake is the emotion that galvanizes his music." The maxi-CD version of the single includes a live cover of Daniel Miller's "Warm Leatherette", performed on BBC Radio 1. The cover was later included in a collector's edition of OK Cowboy. The song appears in the EA video games FIFA 06 and Need for Speed: Carbon (plays only when driving a tuner car). It also features in Riders Republic, developed by Ubisoft Annecy. It is also used as a catwalk soundtrack for Versace Fall/Winter 2005 show.