female
Alicent Hightower was a member of House Hightower who became the second wife to King Viserys I Targaryen. She was the daughter of Ser Otto Hightower, who had been Hand of the King to Jaehaerys I, Viserys I, and later his grandson Aegon II.
Alicent Hightower
Anne Boleyn
for Anne Boleyn in Six: The Musical- Multifandom Version
Suggested by mr95
Again, no real people and no gender-bending the characters. If fictional characters put on a production of Six, who would play the queens?