In a nightmarish crucible orchestrated by Mister Sinister, the Marvel Universe's most exquisite and powerful women are abducted, forcibly infected with a mind-shattering virus that unleashes their deepest primal depravities—turning them into gleeful, sexually sadistic monsters who revel in torturing and butchering one another in an orgiastic hyperviolent deathmatch, all broadcast for Sinister's ecstatic, voyeuristic arousal as he harvests their agony for his ultimate evolution experiment.