The once-ragtag 3rd Street Saints become media superstars, but a botched bank heist throws them into a bloody war with the powerful Syndicate crime family in their new base, Steelport, forcing the Saints to rebuild from scratch, take over the city's gangs (Morningstar, Luchadores, Deckers), and seek revenge after presumed death of Johnny Gat. It's a chaotic, open-world action-adventure focused on outlandish gang warfare and establishing dominance through mayhem.