It has been five years since the events of the original Saints Row. Following the sudden disappearance of founder Julius, the 3rd Street Saints fell apart. In its place, three new gangs divide up Stilwater: the Brotherhood, an outlaw gang specializing in arms trafficking, the Ronin, a Japanese bosozoku gang that runs a network of casinos, porn distribution rings and strip clubs, and the Sons of Samedi, a Haitian voodoo gang that supplies most of the city's drugs. Johnny Gat, Julius's former chief lieutenant, is charged with 387 counts of murder and faces the death penalty. His girlfriend Aisha, despite having been forced to fake her death in the previous game, has become a record producer in her own right. After the events of the first game, the Ultor Corporation has taken over the old Saints Row district and converted it into their own personal financial fiefdom. The other remaining Saints have abandoned the gang; Dex is now a security consultant for Ultor, and Troy, who was responsible for gang's downfall, has been named the new Chief of Police.
