Rosemary and Guy Woodhouse move into an apartment in an opulent but gothic building in Manhattan. Their landlord, Edward "Hutch" Hutchins, attempts to dissuade them: the building has an unsavory history. They discover that their neighbors are a very friendly elderly couple, Roman and Minnie Castevet, and Guy starts spending a great deal of time with them. Soon, strange things start to happen: a young woman Rosemary meets in the laundry room seems to commit suicide, Rosemary has strange dreams and hears strange noises, and Guy becomes remote and distant. Then Rosemary gets pregnant and begins to suspect that her neighbors have special plans for her child.
