When a failed nuclear fusion experiment results in an explosion that kills his wife, Dr. Otto Octavius (Alfred Molina) is transformed into Dr. Octopus, a cyborg with deadly metal tentacles. Doc Ock blames Spider-Man (Tobey Maguire) for the accident and seeks revenge. Meanwhile, Spidey's alter ego, Peter Parker, faces fading powers and self-doubt. Complicating matters are his best friend's (James Franco) hatred for Spider-Man and his true love's (Kirsten Dunst) sudden engagement to another man.
Add actors/actresses and cast the roles/films/series that they were rumored, considered, offered, negotiated, auditioned, turned down, and/or originally casted before getting recasted. (Please double-check in research.)
