Professor Utonium creates a mixture of sugar, spice, and everything nice in hope of producing the "perfect little girl" to improve Townsville, a city plagued by crime and injustice. He is shoved by his laboratory assistant, the destructive chimpanzee Jojo, causing him to accidentally break and spill a flask of Chemical X into the concoction, which explodes in Jojo's face. The experiment is successful, producing three little girls whom the Professor names Blossom, Bubbles, and Buttercup. He also discovers that the girls have gained superpowers from the added Chemical X. Despite the girls' recklessness with their powers, they all immediately grow to love each other as a family. But while the girls saw love from the Professor, Jojo was abandoned and he had to fend for himself, but because he had high intelligence he concocted a plan to crush the Powerpuff Girls.
