Twenty years have passed since Leon Kennedy saved Ashley Graham from a nightmare she barely survived. Now a seasoned DSO agent, Ashley has dedicated her life to stopping the spread of bioterror… but nothing could prepare her for what’s coming.
When a mysterious outbreak devastates remote regions of Australia, The DSO sends Ashley on a high-stakes mission to investigate, where she's joined by Lieutenant Adrien Hayes. The terrain is harsh, the locals terrified, and the horrors she faces are unlike anything she’s encountered before. Twisted creatures, rogue bioweapons, and the enigmatic Dr. Rainer Volkov—a former Umbrella scientist obsessed with forcing humanity to evolve through infection—push Ashley and Adrien to the edge.
Meanwhile, B.S.A.A. Co-Captain Jill Valentine arrives to the island, ready to shut down the scientist's plans by any means necessary.