With the dark memories of a troubled childhood at the Umbrella Corporation's Raccoon City Orphanage still haunting her mind, Claire Redfield returns to her now decaying hometown. However, as Claire reunites with her estranged brother Chris, the entire city suffers an all-out outbreak of the deadly T-virus: an engineered bioweapon inducing blind cannibalistic delirium in humans. Now, with the city plunged into chaos, Claire, Chris, and a handful of police officers have only a few hours to solve the mystery of the remote Spencer Mansion and find a way out of the zombie-infested town. But the city is swarming with the unstoppable monstrosities of the nefarious pharmaceutical organisation. Can the uninfected survivors escape a fate worse than death?