Ethan Winters receives a mysterious message from his wife Mia, who has been missing for three years. Following the trail, he arrives at a ruined plantation in Dulvey, Louisiana, where he meets the Baker family, sadistic and deformed hosts who welcome him to hell. Ethan will have to fight for his life and for Mia's, while discovering the dark secrets hidden in the house and the connection with the Umbrella corporation, responsible for the creation of biological weapons that have unleashed the zombie apocalypse.
