After escape from Spain, Leon returns to America but a awful surprise waits for him. 5 years later, he's in a unknown zone trying to survive as he intends to discover what's going on. Meanwhile, Chris, his sister Claire are in a special mission that leads them to the same place. A clash make agent Hunk to look a way to get out of a risk place near to Racoon city's ruins and now all of them has to fight and find a way out of the place where they are. They must to know to survive for their own only what they have at hand. Scary woods, lonely mountains, dark ruins and abandoned houses and mansions, legions of undeads, monsters and old enemies looking for revenge are part of many of the things they'll have to deal with as they try to find a way to escape and discover a great conspiracy created for Umbrella to destroy the world everything they once believed
