Pamela Isley had everything to remain an innocent assistant, too shy and afraid to rebel, but everything changed that night. Witness of a crime made by her superior, Doctor Woodrue, Pamela wanted to flee but he tried to kill her by pushing her into the result of their joint work. However, what came out later was much worse. Possessing now great powers of seduction and being able to control the plants, Pamela decided never to let herself be done again and went on a vendetta against all those who harmed her by taking the name of Poison Ivy !