Dexter is the main character and protagonist of Dexter's Laboratory. He is a boy genius who has a secret laboratory. His intelligence makes him the brains of the family and he is one of the world's greatest inventors, having created countless weird and amazing machines and experiments. He is always working on new inventions and creations every day, but his sister Dee Dee is always breaking into his lab and destroying his work. The daily events surrounding Dexter's life mainly revolve around his relationship with his sister and everything that happens between the two.
Pibby is ripped out of her safe, preschool world and thrown into unknown lands by an powerful foe controlling his puppets. She has to grow up, learn, and become a badass to stop the cartoon apocalypse and the powerful foe.