Ned's Declassified School Survival Guide follows the lives of Ned Bigby, Jennifer "Moze" Mosely, and Simon "Cookie" Nelson-Cook. The first season takes place during the first semester of seventh grade, the second season covers the second semester of seventh grade, and third season takes place during eighth grade. Throughout the series, Ned builds up a number of 'tips' for his "survival guide", and uses the tips to help himself and his classmates cope with the standard struggles of middle school. Each individual episode relates to a topic in the guide, such as popularity, grades, or sports, as well as developing other plots (such as Ned's love life) throughout.